解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Intravascular malignant lymphomatosis (IML), so-called malignant angioendotheliomatosis, was found in lumbosacral spinal cord and nerve roots of a 78-year-old women who died one month after the onset of symptoms. With regard to the majority of the 37 reviewed neurological cases in the literature, this report is unusua...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00
abstract::We describe the clinical and neuropathologic features of a patient complaining of increased intracranial pressure lasting over two years. Brain CT showed three cystic lesions in the supratentorial regions. Autopsy disclosed multiple small glio vascular abnormalities, in some instances connected with a cystic cavity. T...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::We report three siblings (two boys and girl) with familial (autosomal recessive) infantile olivopontocerebellar atrophy (OPCA) associated with lower motoneuron involvement. Brain autopsy findings in two of the children revealed a multisystem degeneration characterized by marked hypoplasia of phylogenetically new parts...
journal_title:Clinical neuropathology
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::The authors describe a case of a 38-year-old woman suffering from long-standing epigastric pain, abdominal fullness and vomiting due to functional alteration of gastroduodenal motility. Following a surgical procedure, a supraventricular tachyarrhythmia and hemodynamic disturbances suddenly appeared and led to death in...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::A 60-year-old man with massive subarachnoid hemorrhage is reported. Radiologically, bilateral occlusion of the internal carotid arteries and multiple cerebral aneurysms of the saccular type were detected. Postmortem examination revealed that the internal carotid arteries were markedly diminutive and completely occlude...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is a devastating systemic atrophy affecting the upper and lower motor neurons. The etiology is unknown, but one theory of pathogenesis supposes that the motor system is affected by abnormal immune responses. We have studied the prevalence and extent of lymphocytic infiltration, prev...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::The clinical and pathological findings in a 58-year-old Japanese man suffering from type III Machado-Joseph disease are reported. The patient became affected at the age of 50 years and presented cerebellar ataxia, progressive external ophthalmoplegia and muscular atrophy, although extrapyramidal signs were never detec...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1989-05-01 00:00:00
abstract::Some patients with the acquired immunodeficiency syndrome (AIDS) have long-tract degeneration in the spinal cord. Spinal-cord sections showing degeneration were immunoreactive in 13 of 17 AIDS patients using rabbit antiserum to whole disrupted human immunodeficiency virus (HIV) or a mouse monoclonal antibody to HIV co...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Three patients with multiple articular deformities due to arthrogryposis multiplex congenita (AMC) are presented. All had severe thalamic and tegmental degenerations with glial scars and shrunken ferruginated neurons; one had also unilateral porencephaly and polymicrogyri. The character and the pattern of the lesions ...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract::Clinically benign and clinically silent multiple sclerosis is now recognized. The corresponding plaques of demyelination in such cases are usually located in silent areas of the brain. We report a case where a solitary 3 x 3 mm plaque of demyelination was incidentally found in the medulla oblongata at autopsy. Althoug...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1988-09-01 00:00:00
abstract::This clinicopathologic study concerns 15 cases of hemangiopericytoma of the meninges (so-called hemangiopericytic meningioma) among approximately 300 examined cases. Ages of the patients at the first surgery ranged from 25 to 67 years, with a median of 44 years. According to follow-up information, 9 of the 15 died bet...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1988-05-01 00:00:00
abstract::A quantitative and qualitative Golgi comparison of the visual cortex from two agyric brains and of two age-matched controls is reported. In the camera lucida drawings, most pyramidal cells were oriented vertically to the pial surface in the external cellular layer, frequently with their apical dendrites directed towar...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1988-05-01 00:00:00
abstract::A retrospective study of 397 human meningiomas revealed microcystic and cystic changes in about 10% of tumors, predominantly meningiomas of the meningotheliomatous subtype. The biological behavior of these tumors corresponded to those of meningiomas in general, while one tumor singled out from the microcystic variant ...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::In order to compare a group of patients with a polymyositis (PM) to a control group, 28 cases of primary myopathies were examined by morphometry with regard to differences between central and peripheral muscle fibers in muscle fascicles. A significant difference in favor of peripheral muscle fibers, i.e., a peripheral...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::One case of a non-progressive congenital neuropathy is reported. Clinical findings included subtotal analgesia, and diminished temperature, vibration and proprioceptive sense in arms and legs. The sensory nerve action potentials were absent. Autonomic dysfunctions were restricted to tonic pupils. Sural nerve biopsy ta...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1986-09-01 00:00:00
abstract::The acquired immunodeficiency syndrome (AIDS) is characterized by a severe idiopathic deficiency in T-cell mediated immunity. Homosexuals, intravenous drug abusers and Haitians are predominantly affected, predisposing them to opportunistic infections and neoplasms. In this study, the central nervous system (CNS) was e...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::A 33-year-old man had a multinodular tumor on his left index finger. Microscopy revealed a plexiform nerve sheath tumor resembling schwannoma. Including this case, 11 patients from 9 to 39 years old, have been reported with plexiform schwannoma. One patient had von Recklinghausen's neurofibromatosis, and all but one w...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1985-11-01 00:00:00
abstract::This paper concerns the use of the fluorescent cytostatic compound doxorubicin (adriamycin) as a simple and reliable staining technique for nuclear DNA on tissue sections, isolated cell smears and imprint preparations. This method can be applied successfully to formalin-fixed, paraffin-embedded specimens of human brai...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1985-09-01 00:00:00
abstract::A comparative study of the ultrastructure of two cases of ecchordosis physaliphora and of two chordomas demonstrated outstanding similarities in the cells composing these two entities. Chordoma cells possessed a more prominent Golgi apparatus, an endoplasmic reticulum-mitochondria complex, plasmalemmal infoldings, nuc...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::Immunoreactivity of tumor cells for glial fibrillary acidic protein (GFAP) is usually regarded as sign of astrocytic histogenesis and/or differentiation. The present study aimed at a systematic evaluation of the significance of GFAP-containing cells in primitive neuroectodermal tumors (PNETs) with special reference to...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Polar spongioblastomas are rare, histologically distinctive glial neoplasms that have been reported to involve the brain stem, third ventricle, aqueduct, and fourth ventricle. In this case report we describe a polar spongioblastoma of the cervical spinal cord in a patient who has survived 2 1/2 years without evidence ...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1984-09-01 00:00:00
abstract::A two year and ten-month-old girl with cerebello-brain stem leukodystrophy is presented. She was hypotonic with spasticity and showed delayed motor development until she was twelve months old, when regression of motor activities began. Progressive hypotonia, dysphagia and fatal respiratory abnormalities developed. Aud...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1984-07-01 00:00:00
abstract::Cutaneous argyria was diagnosed in a 59-year-old woman. Manic depressive psychosis developed at about the same or a short time thereafter. The patient died 6 years later from a ruptured aortic aneurysm. At autopsy silver deposits were seen in skin, mucous membranes, heart, kidney, and liver. In the central nervous sys...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Temporal lobe tissues from seven patients with drug refractory complex partial seizures were extensively examined using both light and electron microscopy in combination with certain computer techniques. Four of these cases had mesial sclerosis, whereas three cases had no demonstrable lesions in the hippocampus as det...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Myoencephalopathies with abnormal mitochondria comprise a heterogeneous group of diseases and syndromes with a large diversity of clinical signs. Thus, their identification and classification pose many difficulties. The underlying biochemical disorders of energy metabolism evoke non-specific structural alterations of ...
journal_title:Clinical neuropathology
pub_type: 杂志文章,评审
doi:
更新日期:1983-01-01 00:00:00
abstract::This is a case report of a male infant who was hypotonic at birth, failed to maintain his respiratory effort, and despite ventilation died at 27 days of age. Infrequent fetal movements were noted and the possibility of a neuromuscular disorder was suggested antenatally. Electromyography in the neonatal period was indi...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Multiple vascular occlusions are frequently found in the leptomeningeal arteries over watershed infarcts in the brain. These occlusions have largely been interpreted as thrombi secondary to slowing of the blood flow. This report suggests that most of the occlusions are microemboli, which may lodge preferentially in th...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Observations on two patients from unrelated families are reported. Both patients were 32 years old and suffered from a congenital affection of the skeletal muscles. In one (case 2) congenital paresis of the dilator muscle of pupil and cardiomyopathy were also present. In both cases muscle biopsy showed pathologic vari...
journal_title:Clinical neuropathology
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00